SETBP1 Society is pleased to share the funding opportunity offered by the 2023 Million Dollar Bike Ride Grant Program sponsored by the University of Pennsylvania Orphan Disease Center! They are NOW ACCEPTING LETTERS of INTEREST to apply for one $88,740 SETBP1 Haploinsufficiency Disorder research grant. These funds were made possible by the amazing fundraising efforts of our SETBP1Strong Team. The purpose of this RFA is to promote understanding of underlying disease mechanisms and pre-clinical development of potential therapies and tools for SETBP1 haploinsufficiency disorder.

Letters of Interest (LOIs) are due by Friday, September 15, 2023 by 8pm (EST)!

SETBP1 Haploinsufficiency Disorder Grant Specifics: The purpose of this RFA is to promote understanding of underlying disease mechanisms and pre-clinical development of potential therapies and tools for SETBP1 haploinsufficiency disorder. One $88,740 grant available. Areas of interest include, but are not limited to:
-Identifying molecular pathways involved in this disease
-Investigating repurposing of existing FDA approved drugs as a treatment for SETBP1-HD
-Identifying novel drugs or therapies for SETBP1-HD
-Investigating language, cognitive, and attention clinical profiles through natural history studies to further delineate the SETBP1 disorder phenotype and develop diagnostic and/or predictive biomarkers for clinical trials with a preference for virtual administration with multi-language support

In addition, applicants are encouraged to collaborate with existing SETBP1 researchers and to leverage existing disease models (e.g. animal models at JAX, patient-derived cell models at SFARI biorepository, etc.) to assess therapeutic impact. This grant is made possible by Team SETBP1Strong and SETBP1 Society.

Want to learn more? Check out the 2023 MDBR Grant Program details!